Shalina Healthcare

Diproson

Diproson is used where topical corticosteroid therpay is considered the best treatment: contact eczema, atopic dermatitis, lichen

• Cream

• Lotion

Indications

• Specific indications where topical corticosteroid therpay is considered the best treatment: contact eczema, atopic dermatitis, lichen
• Indications where corticosteroid therapy is one of the common treatments: seborrhoeic dermatitis (except the face), psoriasis, lichen, statis dermatitis, non-parasitic prurigo, lupus erythematous, dyshydrosis
• Particular brief short-term applications: insect stings, parasitic prurigo after aetiological treatment

Pharmacological Class

Dermo-corticosteroid

Pharmacological Properties

Anti-inflammatory, antipuritic, antiallergic

Mechanism of Action

• Anti-inflammatory effect: dermocorticosteroids anatagonise vascular permeability and polymorph migration.
• Immunological effect: they act on the four types of immunological reactions. Their effect on type IV (allergic contact dermatitis) is the most significant in dermatology
• Antimicotic effect: they reduce the level of DNA synthesis and cell division: this is the mechanism of action that operates in psoriasis

Side Effects

Telangiectasia, stretch marks, bruising purpura, skin vulnerability, drying of the skin, folliculitis, atrophy, excoriation and skin depigmentation. These effects are rare in short term treatment.

Contradictions

• Hypersensitivity to one of the component
• Primitive bacterial, viral, fungal or parasitic infections
• Ulcerous lesions
• Application to the eyelids (risk of glaucoma)

Observations

• An increase in the number of daily applications may worsen the undesirable effects without improving the therapeutic effects
• It is recommended that not more than 30g / week be used of this highly potent corticosteroid skin preparation
• Prolonged use of corticosteroids on the face at high dose runs the risk of onset of corticosteroid-induced dermatitis. Paradoxically corticosteroid sensitivity will rebound after each discontinuation