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Epiderm
Epiderm is effective in the treatment of various skin infections, such as ringworm, otitis externa, seborrhoeic dermatitis, contact dermatitis, eczemas, psoriasis and athlete's foot
• Lotion
• Cream
Indications
• Epiderm cream/lotion is effective for various types of skin infections such as tinea infections of the skin (ringworm), otitis externa, seborrhoeic dermatitis, contact dermatitis, eczemas, psoriasis, athlete's foot, anal & vulval pruritis.
Pharmacological Class
• Betamethasone dipropionate is a corticosteroid, Gentamicin sulphate is an antibacterial - a mixture of the sulphates of antimicrobial substances produced by micromonospora purpurea, Tolnaftate is an antifungal derived from thiocarbamate, Iodochlorhydroxyquinoline is a halogenated hydroxyquinolone.
Pharmacological Properties
• Antifungal, anti-inflammatory & antibacterial.
Mechanism of Action
Epiderm cream contains a combination of drugs. Betamethasone is effective for corticosteroid-responsive dermatoses because of their anti-inflammatory, anti-pruritic, and vasoconstrictive actions. Gentamicin is an antibiotic that inhibits bacterial growth while tolnaftate is an anti fungal. This combination helps to make Epiderm Cream/Lotion effective in skin conditions resulting from different etiologies. Iodochlorhydroxyquinoline is an antibacterial and antifungal agent.
Side Effects
• Generally safe. Long, continuous treatment may cause atrophic skin changes leading to thinning, loss of elasticity, dilatation of superficial blood vessels, telangiectasiae and ecchymoses.
Contradictions
Epiderm cream/lotion is contraindicated in patients with hypersensitivity reactions to any of the components of this preparation. It is also contraindicated in the treatment of herpes simplex, vaccina or varicella & in pregnancy.
Observations
• Abrupt withdrawal after prolonged therapy may lead to rebound exacerbation of the disease, hence withdraw gradually.
Shalina
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