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Our Categories Our Therapeutic Indexes Our Brands Recent Developments Gliben Gliben is used in the treatment of non-insulin dependent Diabetes Mellitus (type II, maturity-onset diabetes) • Tablets Indications • The treatment of Non-insulin Dependent Diabetes Mellitus (type II, maturity-onset diabetes) Pharmacological Class Glibenclamide- 2nd Generation sulfonylurea class Pharmacological Properties Antidiabetic Mechanism of Action •Gliben appears to lower the blood glucose acutely by stimulating the release of insulin from the pancreas, an effect dependent upon functioning beta cells in the pancreatic islets Side Effects • Visual disturbance, • Nausea,Epigastric bloating, • Diarrhoea, Skin reactions, Photosensitivity, • Cross sensitivity to sulphonamide its derivative • Vasculitis & hepatic disorders Contradictions Subject hypersensitivity to Glibenclamide & Diabetic ketoacidosis, with or without coma Observations Not to be used in severe liver or kidney dysfunction.

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