Shalina Healthcare

Paludose

Paludose is effective against all forms of malaria, including severe malaria, cerebral malaria and malaria resistant to several drugs.

• Tablets

Indications

Effective against all forms of malaria, including severe malaria, cerebral malaria and malaria resistant to several drugs

Pharmacological Class

Artemisinine derivative

Pharmacological Properties

Mainly blood schizonticide

Mechanism of Action

• A reduction in nucleic acid synthesis resulting in the parasite's protein synthesis inhibition
• Destruction of the parasite's membrane

Side Effects

At therapeutic doses, the drug is well tolerated. At high doses, there have been reports of gastrointestinal disorders, dizziness, neutropenia, elevated enzyme values and bradycardia in some patients

Contradictions

Pregnancy, unless otherwise advised by the doctor

Observations

As the levels of recurrence are high with dihydroartemisinine treatment, it is recommended that it be combined with another anti-malarial (e.g. mefloquine)