Alpha Beta Arteether
Alpha-Beta Arteether Injection is highly effective against severe and complicated malaria, ensures rapid control in falciparum malaria
Alpha Beta Arteether Injection
|Alpha Beta Arteether
Molecule: Alpha Beta Arteether
Formulation: Alpha Beta Arteether 150mg/225mg Injection
Packaging Unit: A-B Arteether Injection 150mg: Pack of 3 x 2ml. A-B Arteether Injection 225mg: Pack of 3 x 3ml.
Dosage: Adult - 150mg i.e. 1 ampoule of b arteether once daily for 3 consecutive days, Children - 3mg/Kg per day administered by intramuscular injection over a 3-day period
Severe malaria including cerebral malaria & as a second line drug in chloroquine resistant malaria cases only.
Mechanism Of Action
Alpha-Beta Arteether is a fast acting blood schizonticidal agent for P. falciparum malaria at the erythrocytic stage. α-β Arteether is concentrated in parasitized erytrocytes. The functional group responsible for antimalarial activity of Alpha-Beta Arteether is endoperoxide bridge which inhibits the protein synthesis and alters the ribosomal organization and endoplasmic reticulum.
Alpha-Beta Arteether injection is contraindicated in patients hypersensitive to artemisinin derivatives.