Alpha Beta Arteether

Posted September 23, 2018

Alpha Beta Arteether

Alpha-Beta Arteether Injection is highly effective against severe and complicated malaria, ensures rapid control in falciparum malaria

Product	Molecule
Alpha Beta Arteether Injection	Alpha Beta Arteether

Molecule: Alpha Beta Arteether

Formulation: Alpha Beta Arteether 150mg/225mg Injection

Packaging Unit: A-B Arteether Injection 150mg: Pack of 3 x 2ml. A-B Arteether Injection 225mg: Pack of 3 x 3ml.

Dosage: Adult - 150mg i.e. 1 ampoule of b arteether once daily for 3 consecutive days, Children - 3mg/Kg per day administered by intramuscular injection over a 3-day period

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Indications

Severe malaria including cerebral malaria & as a second line drug in chloroquine resistant malaria cases only.

Pharmacological Class

Pharmacological Properties

Mechanism Of Action

Alpha-Beta Arteether is a fast acting blood schizonticidal agent for P. falciparum malaria at the erythrocytic stage. α-β Arteether is concentrated in parasitized erytrocytes. The functional group responsible for antimalarial activity of Alpha-Beta Arteether is endoperoxide bridge which inhibits the protein synthesis and alters the ribosomal organization and endoplasmic reticulum.

Side Effects

Contraindications

Alpha-Beta Arteether injection is contraindicated in patients hypersensitive to artemisinin derivatives.

Observations