Amlox

Posted September 24, 2018

Amlox

Amlox is in a group of drugs called calcium channel blockers. Amlox is used in the treatment of hypertension, chronic stable angina and vasospastic angina

Product	Molecule
Amlox Tablets	Amlodipine

Molecule: Amlodipine

Formulation: Amlodipine 5mg/10mg Tablets

Packaging Unit: 30 Tablets

Dosage: Adult: Initially, 5mg once daily increased to 10mg once daily if necessary. Elderly: Initial dose: 2.5mg once daily.

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Indications

Hypertension, stable angina and prinzmetal's angina.

Pharmacological Class

Selective dihydropyridine derivative calcium-channel blockers.

Pharmacological Properties

Anti-angina, Antihypertensive.

Mechanism Of Action

Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Calcium into the voltage sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients with vasospastic angina.

Side Effects

Headache, peripheral oedema, fatigue, somnolence, nausea, abdominal pain, flushing, dyspepsia, palpitations, dizziness. Rarely pruritus, rash, dyspnoea, asthenia, muscle cramps. Hypotension, bradycardia, conductive system delay and CCF.

Contraindications

Known hypersensitivity to dihydropyridines.

Observations

May be taken with or without food.