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Amoxy

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Amoxy

Amoxy is an antibiotic useful for the treatment of wide range of infections, including the respiratory tract, genito-urinary tract, gastrointestinal tract and skin
Product Molecule
Amoxy Capsules
Amoxicillin
Amoxy Dry Syrup
Amoxicillin
Amoxy Injectables
Amoxicillin
Indications
Infections of the ear, nose, and throat - due to Streptococcus spp. ( α and β-hemolytic strains only), S. pneumoniae, Staphylococcus spp. or H. influenzae. Infections of the genitourinary tract - due to E. coli, P.mirabilis or E. Faecalis. Infections of the skin and skin structure - due to Streptococcus spp. (α and β-hemolytic strains only), Staphylococcus spp. or E. Coli. Infections of the lower respiratory tract - due to Streptococcus spp. (α and β-hemolytic strains only), S. Pneumoniae, Staphylococcus spp., or H. Influenzae. Gonorrhea, acute uncomplicated (ano-genital and Urethral infections) - due to N. Gonorrhea (males and females). H. Pylori eradication to reduce the risk of duodenal ulcer recurrence.
Pharmacological Class
Antibiotic: Semi-synthetic penicillin
Pharmacological Properties
Antibiotic
Mechanism Of Action
Amoxicillin is derivative of ampicillin and has similar antibacterial spectrum (certain gram-positive and gram-negative organisms); similar bactericidal action as penicillin; acts on susceptible bacteria during multiplication stage by inhibiting cell wall mucopeptide biosynthesis; superior bioavailability and stability to gastric acid and has broader spectrum of activity than penicillin; less active than penicillin against Streptococcus pneumococcus; penicillin-resistant strains also resistant to amoxicillin, but higher doses may be effective; more effective against gram-negative organisms (eg, N meningitidis, H influenzae) than penicillin.
Side Effects
Hyperactivity, agitation, insomnia, dizziness; maculopapular rash, exfoliative dermatitis, urticaria, hypersensitivity vasculitis, diarrhea, nausea, vomiting, Anemia, thrombocytopenia, leucopenia, agranulocytosis. Potentially Fatal: Neuromuscular hypersensitivity, Pseudomembranous colitis.
Contraindications
Known hypersensitivity to penicillins.
Observations
May be taken with or without food. (May be taken with food for better absorption & to reduce GI discomfort). Probenecid delays elimination.
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