Erycin contains Erythromycin is one of the most widely used antibiotics, Erythromycin belongs in a group of drugs called macrolide antibiotics
Formulation: Erythromycin 500mg Tablets
Packaging Unit: 10X10 Tablets
Dosage: Adults: 250 mg tablet four times daily in equally spaced doses or one 500 mg tablet every 12 hours. Dosage may be increased up to 4 g per day according to the severity of the infection. However, twice-aday dosing is not recommended when doses larger than 1 g daily are administered. Children: The usual dosage is 30 to 50 mg/kg/day, in equally divided doses. For more severe infections this dosage may be doubled but should not exceed 4 g per day.
Mild to moderate Upper and lower respiratory tract infections caused by Streptococcus pyogenes; Streptococcus pneumonia. Listerosis, pertussis, skin & skin structure infections, diphtheria, intestinal amoebiasis, acute pelvic inflammatory disease.
Mechanism Of Action
Erythromycin acts by inhibition of protein synthesis by binding 50 S ribosomal subunits of susceptible organisms.
Rash, urticaria; nausea, vomiting, GI discomfort; ototoxicity; central neurotoxicity; agranulocytosis; arrhythmias; pancreatitis. Potentially Fatal: Hepatotoxicity, cholestatic jaundice; raised serum transaminases; eosinophilia.
Erythromycin is contraindicated in patients with known hypersensitivity to this antibiotic, porphyria, hepatic impairment, pregnancy
Should be taken on an empty stomach. (Best taken on an empty stomach at least 2 hours before meals). May antagonise therapeutic effects of lincomycin and clindamycin. Concurrent usage may lead to increased absorption of alcohol. Potentially Fatal: May potentiate actions of neuromuscular blockers, oral anticoagulants, ciclosporin, theophylline. Terfenadine, astemizole, cisapride toxicity increased.