fbpx
WorldWide
Contact

Ibucap

 In

Ibucap

Pain like dental pain, headache, neuralgia, dysmenorrhoea. Fever, Rheumatism (rheumatoid polyarthritis, ankylosing spondylosis).
Product Molecule
Ibucap Capsule
Ibuprofen, Paracetamol, Caffeine
Ibucap Forte Capsule
Ibuprofen, Paracetamol, Caffeine
Indications
Pain like dental pain, headache, neuralgia, dysmenorrhoea. Fever, Rheumatism (rheumatoid polyarthritis, ankylosing spondylosis).
Pharmacological Class
Ibuprofen: propionic acid derivative Paracetamol: para-aminophenol derivative Caffeine: alkaloid of the xanthin group.
Pharmacological Properties
Analgesic, antipyretic, anti-inflammatory
Mechanism Of Action
Ibuprofen: Inhibits synthesis of prostaglandins in body tissues by inhibiting at least 2 cyclo-oxygenase (COX) isoenzymes, COX-1 and COX-2. May inhibit chemotaxis, alter lymphocyte activity, decrease proinflammatory cytokine activity, and inhibit neutrophil aggregation; these effects may contribute to anti-inflammatory activity. Paracetamol: exhibits analgesic action by peripheral blockage of pain impulse generation. It produces antipyresis by inhibiting the hypothalamic heatregulating centre. Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS. Caffeine: promotes cAMP accumulation by inhibiting phosphodiesterase; increases medullary respiratory center sensitivity to carbon dioxide; may prevent apnea by acting as an adenosine receptor antagonist.
Side Effects
Dyspepsia, heart burn, GI bleeding, rash, asthmatic attacks, thrombocytopenia, drug induced ulcer, drowsiness, hepatic necrosis, renal papillary necrosis, vision disturbances & disorientation; rarely nausea & vomiting can occur. Insomnia, restlessness, nervousness and mild delirium.
Contraindications
Active peptic ulcer, history of hypersensitivity to either component, recent GI bleeding, neonates.
Observations
Food interferes with the rate of Ibuprofen absorption.
Recent Posts