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Napril

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Napril

Napril is an ACE inhibitor, Napril is used to treat high blood pressure (hypertension) and also used in the treatment of congestive heart failure in adults
Product Molecule
Napril Tablets
Enalapril
Indications
Hypertension, heart failure.
Pharmacological Class
ACE (Angiotensin converting enzyme) Inhibitor.
Pharmacological Properties
Antihypertensive.
Mechanism Of Action
Enalapril is de-esterified into the active enalaprilat resulting in potent inhibition of ACE thus leading to reduced levels of angiotensin II and aldosterone. Clinically, blood pressure is reduced, salt and water retention is corrected. Ventricular hypertrophy is reversed.
Side Effects
Initial hypotension may be severe and prolonged. Dizziness, headache, fatigue, persistent dry cough, abnormal taste, lassitude, rash, neutropenia, renal impairment or failure.
Contraindications
Hypersensitivity. history of angioedema due to previous treatment with ACE inhibitors; bilateral renal artery stenosis. Pregnancy.
Observations
May be taken with or without food.
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