Neocin is used in the treatment of cutaneo-mucosal infections, including infected wounds, burns, carbuncles and acne
|Polymixin, Bacitracin, Neomycin
Molecule: Polymixin, Bacitracin, Neomycin
Formulation: Polymixin B Sulphate 5000 Units + Bacitracin Zinc 400 Unit + Neomycin Sulphate 3400 Units Cream
Packaging Unit: 15gm Creams
Dosage: Should be applied to the affected skin three times daily until symptoms have resolved.
Treatment of superficial bacterial infections of the skin due to staphylococci and streptococci.
Polymyxin B - polypeptide antibiotic. Bacitracin - cyclic polypeptide antibiotic. Neomycin - Aminoglycoside antibiotic.
Mechanism Of Action
The anti-infective components in the combination are included to provide action against specific organisms susceptible to them. Polymyxin B sulfate and neomycin sulfate together are considered active against the following microorganisms: Staphylococcus aureus, Escherichia coli, Haemophilus influenzae, Klebsiella-Enterobacter species Neisseria species, and Pseudomonas aeruginosa. Bacitracin Zinc is highly active against gram-positive bacilli and cocci and extends the spectrum to include haemolytic streptococci, thus completing the antibacterial range of NEOCIN ointment. There is overlapping of the bactericidal spectra of these three antibiotics, thereby providing increased activity through combined antibiotic action.
Sensitization, especially to neomycin, may occur with continued or repeated use, causing redness and scaling of the treated area. Prolonged use may result in overgrowth of non-susceptible organisms. Anaphylactic reactions are rare.
Known hypersensitivity to any of the constituents.
Should not be applied to large areas of burned or broken skin, since significant systemic absorption can occur, which may lead to irreversible ototoxicity and renal damage.