Prazole / Omeshal

Posted September 23, 2018

Prazole / Omeshal

Prazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by hyperacidity

Product	Molecule
Prazole Capsules	Omeprazole
Prazole D Capsules	Omeprazole, Domperidone

Molecule: Omeprazole

Formulation: Omeprazole 20mg Capsules

Packaging Unit: 10X10 Capsules

Dosage: 20mg daily as a single dose or 40mg daily in severe cases. Treatment duration: Duodenal ulcers: 4 weeks; gastric ulcers: 8 weeks. Maintenance: 10-20 mg once daily.

View PDF

Molecule: Omeprazole, Domperidone

Formulation: Omeprazole 20mg + Domperidone 10mg Capsules

Packaging Unit: 10 Capsules

Dosage: Adult: 1 capsule twice a day before meals for 4-8 weeks or as directed by the physician.

View PDF

Indications

Peptic ulcer, Duodenal ulcer, Gastro-oesophageal reflux disease, Zollinger-Ellison syndrome, acid related dyspepsia, reflux oesphagitis and heartburn.

Pharmacological Class

Proton pump inhibitor - Benzimidazole derivative.

Pharmacological Properties

Ulcer healing drug

Mechanism Of Action

Prazole suppresses gastric acid secretion by specific inhibition of the enzyme system hydrogen/potassium adenosine triphosphatase (H+/K+ ATPase) present on the secretory surface of the gastric parietal cell.

Side Effects

Diarrhoea, nausea, fatigue, constipation, vomiting, flatulence, acid regurgitation, taste perversion, arthralgia, myalgia, urticaria, dry mouth, dizziness, headache, paraesthesia, abdominal pain, skin rashes, weakness, back pain, upper respiratory infection, cough.

Contraindications

Hypersensitivity to prazole.

Observations

Should be taken before meals. Avoid alcohol (may cause gastric mucosal irritation).