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Quinishal

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Quinishal

Quinishal is indicated mainly in the uncomplicated strains of P. falciparum malaria. Consideration must be given to the WHO guidelines and to local health authorities
Product Molecule
Quinishal Suspension
Quinine
Quinishal Injectables
Quinishal
Indications
Quinishal is indicated mainly in the uncomplicated strains of P. falciparum malaria. Consideration must be given to the WHO guidelines and to local health authorities recommendations based on the prevalence of resistance to antimalarial agents.
Pharmacological Class
Pharmacological Properties
Mechanism Of Action
Quinine is a rapidly acting blood schizontocide. It inhibits protein synthesis by preventing strand separation and therefore DNA replication and transcription to RNA.
Side Effects
Contraindications
Quinine and its salts are contra-indicated in patients with a history of hypersensitivity to quinine and in patients with tinnitus or optic neuritis and especially when this takes the form of cutaneous, angioedematous, visual, or auditory symptoms. Quinine should be discontinued immediately if evidence of haemolysis appears. As quinine has been implicated in precipitating blackwater fever, it is generally contraindicated in patients who have already suffered an attack. Quinine should be avoided in patients with myasthenia gravis, as it may aggravate their condition.
Observations
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