Tanzol
Tanzol contains Albendazole which used for the treatment of pinworm, roundworm, hookworm, whipworm, threadworm and taenia infestations
| Product |
Molecule |
Tanzol Syrup |
Albendazole |
Tanzol Tablets |
Albendazole |
Molecule: Albendazole
Formulation: Albendazole 400mg/10ml Syrup
Packaging Unit: 10ml Suspension
Dosage: The dose of Tanzol for adults and children above 2 years is one tablet or 10ml of suspension (400mg albendazole) as a single dose in suspected or confirmed infestations with Pin worms, Whipworms, Large Roundworms, Hookworms.In case of suspected or confirmed cases of Threadworms, Tapeworms, or Dwarf tapeworms, Tanzol should be used at a dose of one tablet or 10ml suspension once daily for 3 consecutive days. In cases of Dwarf Tapeworms, retreatment in 10-21 days is recommended.
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Molecule: Albendazole
Formulation: Albendazole 400mg Tablets
Packaging Unit: 20 Tablets
Dosage: The dose of Tanzol for adults and children above 2 years is one tablet or 10ml of suspension (400mg Albendazole) as a single dose in suspected or confirmed infestations with Pin worms, Whipworms, Large Roundworms, Hookworms. Tanzol 400mg twice daily for 3 consecutive days is effective in the treatment of patients with mixed worm infestation including infestation with Opisthorchis viverrini and Opisthorchis sinensis. For hydatid cysts: 10mg / kg of body weight / day for 4-8 weeks. For neurocysticercosis: 400mg twice a day for 30 days.
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Indications
Tanzol is indicated for the treatment of parasitic worm infestations (single or mixed) due to: Enterobius vermicularis (Pin worms), Trichuris trichuira (Whipworms), Ascaris lumbricoides (Large Roundworms), Ancylostoma duodenale (Hookworms), Necator americanus (Hookworms), Strongyloides stercoralis (Threadworms), Taenia spp (Tapeworms), Hymenolepis nana (Dwarf tapeworms), Taenia solium (Neurocysticercosis), Echinococcus granulosus (Hydatid cysts).
Pharmacological Class
Benzimidazole derivative
Pharmacological Properties
Potent broad spectrum anthelmintic
Mechanism Of Action
Tanzol selectively blocks the glucose uptake by an adult helminthes in the intestine & their tissue dwelling larvae. Inhibition of glucose uptake leads to endogenous depletion of glycogen stored within the parasite. This in turn causes a decrease in the formation of adenosine triphosphate. By this mechanism, the drug slowly depletes the energy levels of the susceptible parasites.
Side Effects
Use of large doses of Tanzol can cause adverse effects like allergic reactions, raised liver enzyme values, alopecia, bone marrow depression etc. Side effects of Tanzol include transient abdominal pain and diarrhea, dizziness, nausea, constipation, dry mouth etc.
Contraindications
Tanzol is contraindicated in pregnancy and in patients with known hypersensitivity to albendazole.
Observations
Should be taken with food.
